Guys, sharing this FYI just in case anyone may be interested (or possibly know someone who could benefit from knowing this kind of information). It's from an Ivermectin friendly source.

It may be (i.e. 'NOT a doctor/NOT advice' :) that some who take IVM should possibly avoid taking certain other common treatments at the same time, including chloroquine/hydroxychloroquine.

Full data is at the link, which also cautions about letting certain pets (let alone children) somehow inadvertantly encounter IVM.

But following are some drugs they say may/may not cause certain rare and/or transient reactions if taken together with IVM:

http://www.thecompleteguidetohealth.com/ivermectincautions.html

IvermectinCautions - The Complete Guide To Health .com

Ivermectin can be given either by mouth or injection. It does not readily cross the blood–brain barrier of mammals due to the presence of P-glycoprotein, (the MDR1 gene mutation affects function of this protein)

"It is therefore questionable whether any of the neurological sequelae associated with administration of ivermectin are directly related to the drug and therefore it seems unlikely that any alterations in the pharmacokinetics of ivermectin for whatever reason would result in a more severe adverse reaction."

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147658/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147658/pdf/1475-2883-2-S1-S8.pdf

ivermectin_-does_p-glycoprotein_play_a_role_in_neurotoxicity.pdf Download File

Drugs that inhibit CYP3A4 enzymes often also inhibit P-glycoprotein transport, so the risk of increased absorption past the blood-brain barrier exists when ivermectin is administered along with other CYP3A4 inhibitors.

These drugs include statins, HIV protease inhibitors, many calcium channel blockers, and glucocorticoids such as dexamethasone, lidocaine, and the benzodiazepines….

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DRUG INTERACTIONS:

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EVERYONE should consult with an appropriate health care practitioner before taking ivermectin.

People who consume any of the medications listed below should be extra careful and take special precautions as these drugs are believed to interact with ivermectin.

The list below is NOT meant to be a complete list. It is simply a quick guide to alert those who take any of these medications to be extra careful.

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ALCOHOL - do NOT drink alcohol in combination with ivermectin.

Analgesics     Metamizole

Antibacterials    Clarithromycin    Rifabutin    Rifampicin    Rifapentine    Telithromycin

Antiarrhythmics    Quinidine

Anti-coagulant, Anti-platelet and Fibrinolytic    Acenocoumarol    Argatroban    Dipyridamole    Fondaparinux    Heparin    Phenprocoumon    Warfarin

Antidepressants    St. John’s wort

Anticonvulsants     Carbamazepine    Eslicarbazepine    Oxcarbazepine    Phenobarbital (Phenobarbitone)    Phenytoin    Primidone    Rufinamide

**Antifungals **    Griseofulvin    Itraconazole    Ketoconazole

Antipsychotics/Neuroleptics     Thioridazine 

Calcium Channel Blockers    Verapamil

HCV DAAs    Glecaprevir/Pibrentasvir    Ombitasvir/Paritaprevir/r    Ombitasvir/Paritaprevir/r + Dasabuvir

HIV Antiretroviral Therapies    Atazanavir + ritonavir    Atazanavir/cobicistat    Efavirenz    Elvitegravir/Cobi/Emtricitabine/TAF    Elvitegravir/Cobi/Emtricitabine/TDF    Etravirine    Nevirapine

Covid-19 Antiviral Therapies    Atazanavir    Chloroquine    Hydroxychloroquine    Lopinavir/ritonavir

Covid-19 Immune Therapies    Ruxolitinib

Hypertension / Heart Failure Agents    Bosentan    Ranolazine

Immunosuppressants    Ciclosporin

Steroids    Betamethasone

The above list was obtained from Covid19-DrugInteractions.org. Click on the button below for additional information.

CONTRA-INDICATIONS AND DRUG INTERACTIONS

    Additional caution should also be exercised with patients who are currently taking CYP 3A4 or P-gp inhibitor drugs such as:

Amiodarone

Clarithromycin

Cobicistat

Cyclosporine

Diltiazem

Erythromycin

Indinavir

Itraconazole

Ketoconazole

Quinidine

Ritonavir

Spironolactone,

Tacrolimus

Verapamil

SOURCE: https://clinicaltrials.gov/ct2/show/NCT04530474

NOTE: Even after serious overuse/abuse of ivermectin, the symptoms subsided after the patients stopped abusing the medication.