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posted ago by penisse ago by penisse +19 / -0

(1/2) New study: the coronavirus spike protein peptide with the sequence RSAIEDLLFDK can form amyloid-like fibrillar structures & hydrogels!

👉🏻 https://pubs.acs.org/doi/10.1021/acsnano.1c10658

The process is primarily initiated at pH ≈ 4.

A hydrogel is a crosslinked hydrophilic polymer that does not dissolve in water

(2/2) Can this process also happen in vivo? That is not yet known.

At least the spike protein has already been found in lysosomes, which have a pH value of around 4.5:

👉🏻 https://www.biorxiv.org/content/10.1101/2020.12.08.417022v1