Yes to both. These and many more human-made toxins have had a cumulative effect on altering neurological and hormonal balances in humans and animals.

A big one is Fluoride in the water supply and in toothpaste which is now reported to reduce I.Q. and lower testosterone.

The Lady Boys in Thailand can be tied to industrial waste in those areas, especially mercury contamination.

The sweetener Stevia has been found to sterilize both males and females.

There is much more if you care to do the research.