Comments here are correct. While animal studies are to show exactly this risk for toxicity and whether or not a drug should move forward in human trials, they are only “models”. Animals are very different and they are dosed to much higher extremes. With that said, animal study results like these would’ve halted the program for quite some time.

Comments here are correct. While animal studies are to show exactly this risk for toxicity and whether or not a drug should move forward in human trials, they are only “models”. Animals are very different and they are dosed to much higher extremes. With that said, animal