(Of course this is just some public domain info to research further - not specifically ‘medical advice’ :)
However it’s very hopeful research, and quite a few (exceptional) health care practitioners (orthomolecular & naturopathic physicians in particular) know of and use it widely.
……….
Vitamin E in its naturally polarized ‘dextro-' form (natural right-polarized d-alpha tocopherol - vs. dl or the artificial dextro/levo synthetic form) may provide an especially valuable healing environment for vascular and other tissues.
(Also rarely, a few people may not take to Vitamin E as well as others, due to each human’s ‘Biochemical Individuality’ (also important in v- issues!). So staying mindful, and if desired checking w/ your health care people, is nice too.)
Also this Vitamin E delivery form, d-α-tocopheryl polyethylene glycol-succinate (i.e. combined with a particular delivery system that can maximize effects) has been found to be particularly promising for many (!!) potential clinical applications.
Drs. Wilfrid and Evan Shute did extensive research on the myriad range of incredible clinical healing effects of natural d-alpha tocopherol Vitamin E in the 1940’s & on. They were genius brothers, medical pioneers and true healers, who had their own independent lab in Canada; therefore the usual pharma special interests couldn’t fully suppress their research.
If you read Vitamin E labels closely, you can find the natural d-alpha tocopherol form in drugstores. Personally I like the generous 670 mg / 1000 IU softgels. These soft gels of Vitamin E are also effective when applied externally to protect skin and facilitate healing from burns, such as sunburn, etc.
A couple of examples below, can be a starting point for further research:
This first suggestive animal study (involving retinal ischemia), is actually from food production science:
https://www.researchgate.net/publication/7246801_Protective_Effects_of_Vitamin_E_Forms_Alpha-tocopherol_Gamma-tocopherol_and_d-alpha-tocopherol_Polyethylene_Glycol_1000_Succinate_on_Retinal_Edema_During_Ischemia-reperfusion_Injury_in_the_Guinea_Pig_ Protective Effects of Vitamin E Forms (Alpha-tocopherol, Gamma-tocopherol and d-alpha-tocopherol Polyethylene Glycol 1000 Succinate) on Retinal Edema During Ischemia–reperfusion Injury in the Guinea Pig Retina _ Request PDF
October 2004 International Ophthalmology 25(5-6):283-9
‘The purpose of this study is to provide evidence that free radical damage is a component of retinal ischemia-reperfusion (I/R) injury, and to determine whether alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate (TPGS) can protect the retina from this injury.
[They induced retinal ischemia in lab guinea pigs ………. All the three substances showed statistically significant protection against the formation of retinal edema during ischemia-reperfusion injury.]
The results from these experiments indicate that vitamin E forms have protective effects on the retina during retinal ischemia-reperfusion injury, but, the effects of alpha-tocopherol and TPGS appear to be much greater than that of gamma-tocopherol.
……….
*Journal of Drug Delivery on TPGS:
https://www.tandfonline.com/doi/full/10.1080/10717544.2017.1406561 Full article_ Recent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy
Songwei Tan,Chenming Zou,Wei Zhang,Mingxing Yin,Xueqin Gao &Qing Tang Pages 1831-1842 | Received 28 Sep 2017, Accepted 14 Nov 2017, Published online: 28 Nov 2017
‘As an FDA-approved biocompatible drug excipient, d-α-tocopheryl polyethylene glycol succinate (TPGS) has been widely applied in drug delivery system (DDS). Along with in-depth analyses of TPGS-based DDS,increasingly attractive results have revealed that TPGS is able to act not only as a simple drug carrier but also as an assistant molecule with various bio-functions to improve anticancer efficacy.
In this review, recent advances in TPGS-based DDS are summarized. TPGS can inhibit P-glycoprotein, enhance drug absorption, induce mitochondrial-associated apoptosis or other apoptotic pathways, promote drug penetration and tumor accumulation, and even inhibit tumor metastasis. As a result, many formulations, by using original TPGS, TPGS-drug conjugates or TPGS copolymers, were prepared, and as expected, an enhanced therapeutic effect was achieved…’
(Of course this is just some public domain info to research further - not specifically ‘medical advice’ :)
However it’s very hopeful research, and quite a few (exceptional) health care practitioners (orthomolecular & naturopathic physicians in particular) know of and use it widely.
……….
Vitamin E in its naturally polarized ‘dextro-' form (natural right-polarized d-alpha tocopherol - vs. dl or the artificial dextro/levo synthetic form) may provide an especially valuable healing environment for vascular and other tissues.
(Also rarely, a few people may not take to Vitamin E as well as others, due to each human’s ‘Biochemical Individuality’ (also important in v- issues!). So staying mindful, and if desired checking w/ your health care people, is nice too.)
Also this Vitamin E delivery form, d-α-tocopheryl polyethylene glycol-succinate (i.e. combined with a particular delivery system that can maximize effects) has been found to be particularly promising for many (!!) potential clinical applications.
Drs. Wilfrid and Evan Shute did extensive research on the myriad range of incredible clinical healing effects of natural d-alpha tocopherol Vitamin E in the 1960’s & on. They were genius brothers, medical pioneers and true healers, who had their own independent lab in Canada; therefore the usual pharma special interests couldn’t fully suppress their research.
If you read Vitamin E labels closely, you can find the natural d-alpha tocopherol form in drugstores. Personally I like the generous 670 mg / 1000 IU softgels. These soft gels of Vitamin E are also effective when applied externally to protect skin and facilitate healing from burns, such as sunburn, etc.
A couple of examples below, can be a starting point for further research:
This first suggestive animal study (involving retinal ischemia), is actually from food production science:
https://www.researchgate.net/publication/7246801_Protective_Effects_of_Vitamin_E_Forms_Alpha-tocopherol_Gamma-tocopherol_and_d-alpha-tocopherol_Polyethylene_Glycol_1000_Succinate_on_Retinal_Edema_During_Ischemia-reperfusion_Injury_in_the_Guinea_Pig_ Protective Effects of Vitamin E Forms (Alpha-tocopherol, Gamma-tocopherol and d-alpha-tocopherol Polyethylene Glycol 1000 Succinate) on Retinal Edema During Ischemia–reperfusion Injury in the Guinea Pig Retina _ Request PDF
October 2004 International Ophthalmology 25(5-6):283-9
‘The purpose of this study is to provide evidence that free radical damage is a component of retinal ischemia-reperfusion (I/R) injury, and to determine whether alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate (TPGS) can protect the retina from this injury.
[They induced retinal ischemia in lab guinea pigs ………. All the three substances showed statistically significant protection against the formation of retinal edema during ischemia-reperfusion injury.]
The results from these experiments indicate that vitamin E forms have protective effects on the retina during retinal ischemia-reperfusion injury, but, the effects of alpha-tocopherol and TPGS appear to be much greater than that of gamma-tocopherol.
……….
*Journal of Drug Delivery on TPGS:
https://www.tandfonline.com/doi/full/10.1080/10717544.2017.1406561 Full article_ Recent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy
Songwei Tan,Chenming Zou,Wei Zhang,Mingxing Yin,Xueqin Gao &Qing Tang Pages 1831-1842 | Received 28 Sep 2017, Accepted 14 Nov 2017, Published online: 28 Nov 2017
‘As an FDA-approved biocompatible drug excipient, d-α-tocopheryl polyethylene glycol succinate (TPGS) has been widely applied in drug delivery system (DDS). Along with in-depth analyses of TPGS-based DDS,increasingly attractive results have revealed that TPGS is able to act not only as a simple drug carrier but also as an assistant molecule with various bio-functions to improve anticancer efficacy.
In this review, recent advances in TPGS-based DDS are summarized. TPGS can inhibit P-glycoprotein, enhance drug absorption, induce mitochondrial-associated apoptosis or other apoptotic pathways, promote drug penetration and tumor accumulation, and even inhibit tumor metastasis. As a result, many formulations, by using original TPGS, TPGS-drug conjugates or TPGS copolymers, were prepared, and as expected, an enhanced therapeutic effect was achieved…’
(Of course this is just some public domain info to research further - not specifically ‘medical advice’ :)
However it’s very hopeful research, and quite a few (exceptional) health care practitioners (orthomolecular & naturopathic physicians in particular) know of and use it widely.
……….
Vitamin E in its naturally polarized ‘dextro-‘ form (natural right-polarized d-alpha tocopherol - vs. dl or the artificial dextro/levo synthetic form) may provide an especially valuable healing environment for vascular and other tissues.
(Also rarely, a few people may not take to Vitamin E as well as others, due to each human’s ‘Biochemical Individuality’ (also important in v- issues!). So staying mindful, and if desired checking w/ your health care people, is nice too.)
Also this Vitamin E delivery form, d-α-tocopheryl polyethylene glycol-succinate (i.e. combined with a particular delivery system that can maximize effects) has been found to be particularly promising for many potential clinical applications.
Drs. Willard and Evan Shute did extensive research on the myriad range of incredible clinical healing effects of natural d-alpha tocopherol Vitamin E in the 1960’s & on. They were genius brothers, medical pioneers and true healers, who had their own independent lab in Canada; therefore the usual pharma special interests couldn’t fully suppress their research.
If you read Vitamin E labels closely, you can find the natural d-alpha tocopherol form in drugstores. Personally I like the generous 670 mg / 1000 IU softgels. These soft gels of Vitamin E are also effective when applied externally to protect skin and facilitate healing from burns, such as sunburn, etc.
A couple of examples below, can be a starting point for further research:
This first suggestive animal study (involving retinal ischemia), is actually from food production science:
https://www.researchgate.net/publication/7246801_Protective_Effects_of_Vitamin_E_Forms_Alpha-tocopherol_Gamma-tocopherol_and_d-alpha-tocopherol_Polyethylene_Glycol_1000_Succinate_on_Retinal_Edema_During_Ischemia-reperfusion_Injury_in_the_Guinea_Pig_ Protective Effects of Vitamin E Forms (Alpha-tocopherol, Gamma-tocopherol and d-alpha-tocopherol Polyethylene Glycol 1000 Succinate) on Retinal Edema During Ischemia–reperfusion Injury in the Guinea Pig Retina _ Request PDF
October 2004 International Ophthalmology 25(5-6):283-9
‘The purpose of this study is to provide evidence that free radical damage is a component of retinal ischemia-reperfusion (I/R) injury, and to determine whether alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate (TPGS) can protect the retina from this injury.
[They induced retinal ischemia in lab guinea pigs ………. All the three substances showed statistically significant protection against the formation of retinal edema during ischemia-reperfusion injury.]
The results from these experiments indicate that vitamin E forms have protective effects on the retina during retinal ischemia-reperfusion injury, but, the effects of alpha-tocopherol and TPGS appear to be much greater than that of gamma-tocopherol.
……….
*Journal of Drug Delivery on TPGS:
https://www.tandfonline.com/doi/full/10.1080/10717544.2017.1406561 Full article_ Recent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy
Songwei Tan,Chenming Zou,Wei Zhang,Mingxing Yin,Xueqin Gao &Qing Tang Pages 1831-1842 | Received 28 Sep 2017, Accepted 14 Nov 2017, Published online: 28 Nov 2017
‘As an FDA-approved biocompatible drug excipient, d-α-tocopheryl polyethylene glycol succinate (TPGS) has been widely applied in drug delivery system (DDS). Along with in-depth analyses of TPGS-based DDS,increasingly attractive results have revealed that TPGS is able to act not only as a simple drug carrier but also as an assistant molecule with various bio-functions to improve anticancer efficacy.
In this review, recent advances in TPGS-based DDS are summarized. TPGS can inhibit P-glycoprotein, enhance drug absorption, induce mitochondrial-associated apoptosis or other apoptotic pathways, promote drug penetration and tumor accumulation, and even inhibit tumor metastasis. As a result, many formulations, by using original TPGS, TPGS-drug conjugates or TPGS copolymers, were prepared, and as expected, an enhanced therapeutic effect was achieve…’