Thank you for posting this!

It supports my theory of cancer, general health, and how to live a healty life for most people -- without drugs.

Ivermectin-induced cytostatic autophagy also leads to suppression of tumor growth ...

That is the KEY statement in that entire thing.

It is known that mTOR and AMPK regulate cellular growth and repair.

It is one or the other. One is "on" while the other is "off" and vice versa.

Our bodies are constantly switching from an anabolic state (cellular growth) to a catabolic state (cellular death, repair, and cleansing).

Our bodies need BOTH states in order to be healthy.

In the anabolic state, our muscles grow, but so do our fat cells and everything else. This state is caused by eating food, expecially protein, and anabolic exercise (weight lifting, wind sprints, etc.). This state is switched "on" by mTOR, which is activated by eating and exercise.

In the catabolic state, our body's cells have a chance to repair. The dead or poor-performing cells die off, pathogens that can't survive die off, and our immune system sweeps these bad materials to the liver for processing, where they are either recycled into something else or expelled from the body. This state is caused naturally when we go for periods of time without eating. This state is switched "on" when mTOR switches "off" and AMPK is activated.

Bodybuilders grow muscle by eating frequently and lifting weights. This keeps mTOR activated most of the time. They typically eat healthy and the exercise they get allow nutrients to go into the muscles.

The problem most people have (and some bodybuilders later in life) is they eat frequently throughout the day, do not eat healthy, and do not exercise. So, the nutrients are not as high quality, and they are not directed towards muscle growth but towards fat growth, due to mTOR always being high (by eating constantly throughout the day).

Over time, this overeating (especially of bad foods) causes problems with the old, poor-performing cells not being able to "die off" properly. They then degenerate and this is what the medical industry calls "cancer cell mutation." It is not really what they think it is. My theory is that it is simply these cells staying in the body long past when they should have been swept out by the immune system.

At some point, if a person continues with a poor lifestyle, these cells proliferate. By continuing to constantly eat all day, every day, these cells continue to increase in number because mTOR is constantly activated.

But these cells are not functioning like healthy, new cells would. Therefore, the body is not operating like it should. When the number of cells gets to be too much for the immune system to cleanse, the body gets to a state where it can be stated that the person "has cancer."

We all have cancer cells, but it is only "cancer" when the total number is too large. The fundamental problem is the person does not allow their body to rest from eating. They do not allow their body to go into autophagy often enough or long enough, by deregulating mTOR and activating AMPK (by not eating).

This is why so many people experience health benefits from intermittent fasting. It is also why some people claim improvement in cancer from eating an "alkaline" diet. It is not the acid/alkaline aspect, but rather the fact that less protein reduces the effect of mTOR and allows the body to return back to AMPK-control and autophagy sooner. Intermittent fasting would be even more effective, I suspect.

It looks like ivermectin might be a "short cut" to getting into autophagy, especially for people who don't know about fasting, or for people who are extemely skinny and can't fast (because fasting would cause too much catabolism for very skinny people -- this is why the medical industry warns people with cancer to make sure they eat a lot, but it is only a problem for very skinny people). Most people can fast (and fat people can fast a long time -- that's what the excess fat is for, stored energy for future needs).

This is the ivermectin paper:

https://pubmed.ncbi.nlm.nih.gov/27302166/

This talks specifically about mTOR:

https://www.jci.org/articles/view/73939

This talks about the relationship between mTOR and AMPK:

https://pubmed.ncbi.nlm.nih.gov/22017684/

My basic theory about cancer is that it is simply the body getting overwhelmed with too many underperforming cells, due to the body's inability to cleans (autophagy), and that condition is caused by a combination of (a) too many bad cells building up, which is caused by too much time spent with mTOR activated and too little time spent with AMPK activated, and (b) a weakened immune system, which can be caused by a number of things, including the mTOR/AMPK relationship.

Thank you for posting this!

It supports my theory of cancer, general health, and how to live a healty life for most people -- without drugs.

Ivermectin-induced cytostatic autophagy also leads to suppression of tumor growth ...

That is the KEY statement in that entire thing.

It is known that mTOR and AMPK regulate cellular growth and repair.

It is one or the other. One is "on" while the other is "off" and vice versa.

Our bodies are constantly switching from an anabolic state (cellular growth) to a catabolic state (cellular death, repair, and cleansing).

Our bodies need BOTH states in order to be healthy.

In the anabolic state, our muscles grow, but so do our fat cells and everything else. This state is caused by eating food, expecially protein, and anabolic exercise (weight lifting, wind sprints, etc.). This state is switched "on" by mTOR, which is activated by eating and exercise.

In the catabolic state, our body's cells have a chance to repair. The dead or poor-performing cells die off, pathogens that can't survive die off, and our immune system sweeps these bad materials to the liver for processing, where they are either recycled into something else or expelled from the body. This state is caused naturally when we go for periods of time without eating. This state is switched "on" when mTOR switches "off" and AMPK is activated.

Bodybuilders grow muscle by eating frequently and lifting weights. This keeps mTOR activated most of the time. They typically eat healthy and the exercise they get allow nutrients to go into the muscles.

The problem most people have (and some bodybuilders later in life) is they eat frequently throughout the day, do not eat healthy, and do not exercise. So, the nutrients are not as high quality, and they are not directed towards muscle growth but towards fat growth, due to mTOR always being high (by eating constantly throughout the day).

Over time, this overeating (especially of bad foods) causes problems with the old, poor-performing cells not being able to "die off" properly. They then degenerate and this is what the medical industry calls "cancer cell mutation." It is not really what they think it is. My theory is that it is simply these cells staying in the body long past when they should have been swept out by the immune system.

At some point, if a person continues with a poor lifestyle, these cells proliferate. By continuing to constantly eat all day, every day, these cells continue to increase in number because mTOR is constantly activated.

But these cells are not functioning like healthy, new cells would. Therefore, the body is not operating like it should. When the number of cells gets to be too much for the immune system to cleanse, the body gets to a state where it can be stated that the person "has cancer."

We all have cancer cells, but it is only "cancer" when the total number is too large. The fundamental problem is the person does not allow their body to rest from eating. They do not allow their body to go into autophagy often enough or long enough, by deregulating mTOR and activating AMPK (by not eating).

This is why so many people experience health benefits from intermittent fasting. It is also why some people claim improvement in cancer from eating an "alkaline" diet. It is not the acid/alkaline aspect, but rather the fact that less protein reduces the effect of mTOR and allows the body to return back to AMPK-control and autophagy sooner. Intermittent fasting would be even more effective, I suspect.

It looks like ivermectin might be a "short cut" to getting into autophagy, especially for people who don't know about fasting, or for people who are extemely skinny and can't fast due to cause worse health. Most people can fast (and fat people can fast a long time -- that's what the excess fat is for).

This is the ivermectin paper:

https://pubmed.ncbi.nlm.nih.gov/27302166/

This talks specifically about mTOR:

https://www.jci.org/articles/view/73939

This talks about the relationship between mTOR and AMPK:

https://pubmed.ncbi.nlm.nih.gov/22017684/

My basic theory about cancer is that it is simply the body getting overwhelmed with too many underperforming cells, due to the body's inability to cleans (autophagy), and that condition is caused by a combination of (a) too many bad cells building up, which is caused by too much time spent with mTOR activated and too little time spent with AMPK activated, and (b) a weakened immune system, which can be caused by a number of things, including the mTOR/AMPK relationship.