https://www.cdc.gov/immigrantrefugeehealth/guidelines/overseas-guidelines.html

Precautions and contraindications to presumptive treatment

Children

Albendazole Children <1 year of age should not receive presumptive treatment with albendazole. Further information on use of albendazole in pediatric patients can be found at the CDC, Division of Parasitic Diseases website.Ivermectin Children weighing <15 kg or measuring <90 cm should not receive presumptive treatment with ivermectin. Further information on use of ivermectin in pediatric patients can be found at the CDC, Division of Parasitic Diseases website.Praziquantel The safety of praziquantel has not been established in children <4 years of age or <94 cm in height, so these children should not receive presumptive treatment. Further information on use of praziquantel in pediatric patients can be found at the CDC, Division of Parasitic Diseases website.

Pregnant women

Albendazole Albendazole is currently a category C drug in the United States, and it should not be administered as presumptive treatment for U.S.-bound refugees during any trimester of pregnancy. When a reliable history of the woman’s last menstrual period cannot be obtained, a pregnancy test should be performed. Pregnant women should have presumptive treatment deferred until after they arrive in the United States. Further information on use of albendazole during pregnancy can be found at the CDC, Division of Parasitic Diseases website.Ivermectin Ivermectin is a pregnancy category C drug. This medication should not be administered as a presumptive medication to a pregnant woman. When a reliable history of the woman’s last menstrual period cannot be obtained, a pregnancy test should be performed before presumptive treatment is administered. Further information on use of ivermectin during pregnancy can be found at the CDC, Division of Parasitic Diseases website.Praziquantel Praziquantel is considered a pregnancy category B drug, and WHO recommends the presumptive treatment of pregnant women during any trimester of pregnancy in women from schistosomiasis-endemic areas. Further information on use of praziquantel during pregnancy can be found at the CDC, Division of Parasitic Diseases website.

Women who are breastfeeding

Albendazole Albendazole presumptive therapy may be administered to women who are breastfeeding. Further information on use of albendazole during lactation can be found at the CDC, Division of Parasitic Diseases website.Ivermectin Presumptive treatment with ivermectin should not be administered to women who are breastfeeding during the first week after birth. Further information on use of ivermectin during lactation can be found at the CDC, Division of Parasitic Diseases website.Praziquantel Praziquantel is excreted in low concentrations in human milk. According to WHO guidance for mass prevention campaigns, the use of praziquantel during lactation is safe. 7 For individual patients in clinical settings, praziquantel should be used in breast-feeding women only when the risk to the infant is outweighed by the risk of disease progression in the mother in the absence of treatment. Further information on use of praziquantel during lactation can be found at the CDC, Division of Parasitic Diseases website.