Maybe I'm reading it wrong but the "No outcome was provided for 238 pregnancies" concerns me. Yes, anyone citing 90% mortality is wrong and disingenuous. BUT, I would not put it past Pfizer to hide unwanted outcomes in patients who don't follow up. There were a significant number of patients in the phase 3 clinical trial that just didn't follow up as well.
In other words, the clinical trial for this product was a shit show.
90% out of the known outcomes would make any statistician expect a similar rate in the unknown ones if they were otherwise comparable. Which we have no way of knowing, from this. IF all the rest had no incident at all it would be a wonder. The one way this could reasonably happen would be if all the pregnancy losses came at the same time in fetal development and that was somehow critical. We don't know that either, but I do recall some other news from months ago about a cohort with very high losses in the first trimester. Even normally the very earliest weeks of pregnancy have a high loss rate. Still, it is alarming and unlikely that we are looking at the only losses.
Pfizer is trying to prove their jab is safe with these studies. These are “controlled” studies from a fast tracked novel treatment, not randomized population data. From a company that has the largest criminal fine in history for false claims.
These types of statistica evaluations are intended to be predictive and that goes out the window when the source of the data is suspect.
Maybe I'm reading it wrong but the "No outcome was provided for 238 pregnancies" concerns me. Yes, anyone citing 90% mortality is wrong and disingenuous. BUT, I would not put it past Pfizer to hide unwanted outcomes in patients who don't follow up. There were a significant number of patients in the phase 3 clinical trial that just didn't follow up as well.
In other words, the clinical trial for this product was a shit show.
90% out of the known outcomes would make any statistician expect a similar rate in the unknown ones if they were otherwise comparable. Which we have no way of knowing, from this. IF all the rest had no incident at all it would be a wonder. The one way this could reasonably happen would be if all the pregnancy losses came at the same time in fetal development and that was somehow critical. We don't know that either, but I do recall some other news from months ago about a cohort with very high losses in the first trimester. Even normally the very earliest weeks of pregnancy have a high loss rate. Still, it is alarming and unlikely that we are looking at the only losses.
Pfizer is trying to prove their jab is safe with these studies. These are “controlled” studies from a fast tracked novel treatment, not randomized population data. From a company that has the largest criminal fine in history for false claims.
These types of statistica evaluations are intended to be predictive and that goes out the window when the source of the data is suspect.