Ok, this is anecdotal, but my wife is a G.I. Nurse (Gastro Interology). She has seen multiple cases of otherwise healthy young people (low to mid 20’s) who have had their intestines lose blood flow and become necrotic, some requiring bowel resections and some requiring LIFE-LONG colostomy bags. Why? Because the nicotine dosage levels in the vape can be much higher than cigarettes. And capers tend to hit them very frequently. Nicotine is a vaso-restrictor (it cuts down veinous blood-flow). Your sensitive and finely veined intestines require good blood flow to remain healthy. Frequent high-dosing vapers can literally rot their guts from the inside. This isn’t meant to doom and gloom anyone, but this particular risk almost entirely unknown or reported outside the GI world.