There are numerous reports of adrenochrome being both a psychotropic (mild hallucinogen) and a primary component in schizophrenia. This report from A. Hoffer from 1981 discusses decades of his work in detail. I have not read the whole thing (I just found it to answer your question), but what I am reading matches other research I have found in this topic. Below are a couple quotes of interest:
Hoffer, Osmond and Smythies (1954) suggested that in schizophrenics too much adrenochrome was formed, that it reacted in the body by producing perceptual and thought disorder changes, that it was the schizophrenic endogenous hallucinogen or more accurately the endogenous schizogen. The presence of this aberrant biochemical system would account for many of the physiological and biochemical findings present in many schizophrenic patients if not in all.
Such a drug would be very beneficial in breaking someone's mind, especially in conjunction with the ritual required to obtain it.
At the end he discusses a lack of interest in delving into this area of inquiry despite evidence to support it.
Unfortunately the many leads developed by the adrenochrome hypothesis have been neglected by research institutions for a number of reasons. The critical and hostile attitude of the professional associations and granting agencies discouraged scientists from entering this difficult but challenging field.
It makes sense that evidence of adrenochrome would be sparse given the implications, but it does exist, you just have to look.
Edit: fixed link.
There are numerous reports of adrenochrome being both a psychotropic (mild hallucinogen) and a primary component in schizophrenia. This report from A. Hoffer from 1981 discusses decades of his work in detail. I have not read the whole thing (I just found it to answer your question), but what I am reading matches other research I have found in this topic. Below are a couple quotes of interest:
Hoffer, Osmond and Smythies (1954) suggested that in schizophrenics too much adrenochrome was formed, that it reacted in the body by producing perceptual and thought disorder changes, that it was the schizophrenic endogenous hallucinogen or more accurately the endogenous schizogen. The presence of this aberrant biochemical system would account for many of the physiological and biochemical findings present in many schizophrenic patients if not in all.
Such a drug would be very beneficial in breaking someone's mind, especially in conjunction with the ritual required to obtain it.
At the end he discusses a lack of interest in delving into this area of inquiry despite evidence to support it.
Unfortunately the many leads developed by the adrenochrome hypothesis have been neglected by research institutions for a number of reasons. The critical and hostile attitude of the professional associations and granting agencies discouraged scientists from entering this difficult but challenging field.
It makes sense that evidence of adrenochrome would be sparse given the implications, but it does exist, you just have to look.
There are numerous reports of adrenochrome being both a psychotropic (mild hallucinogen) and a primary component in schizophrenia. This report from A. Hoffer from 1981 discusses decades of his work in detail. I have not read the whole thing (I just found it to answer your question), but what I am reading matches other research I have found in this topic. Below are a couple quotes of interest:
Hoffer, Osmond and Smythies (1954) suggested that in schizophrenics too much adrenochrome was formed, that it reacted in the body by producing perceptual and thought disorder changes, that it was the schizophrenic endogenous hallucinogen or more accurately the endogenous schizogen. The presence of this aberrant biochemical system would account for many of the physiological and biochemical findings present in many schizophrenic patients if not in all.
Such a drug would be very beneficial in breaking someone's mind, especially in conjunction with the ritual required to obtain it.
At the end he discusses a lack of interest in delving into this area of inquiry despite evidence to support it.
Unfortunately the many leads developed by the adrenochrome hypothesis have been neglected by research institutions for a number of reasons. The critical and hostile attitude of the professional associations and granting agencies discouraged scientists from entering this difficult but challenging field.
It makes sense that evidence of adrenochrome would be sparse given the implications, but it does exist, you just have to look.