Oh, I need to mention something important if you have the same problem I do.
Methylene Blue might be the proper treatment.
The active mechanism is as a NO -> NOS inhibitor.
POTS people don't have too much NO or NOS, but the creation of NOS is needed for spikes of norepinephrine.
Spikes of norepinephrine are pronounced in people with POTS, which is why many complain that caffeine makes them sleepy (it does for me).
The caffeine spikes adrenaline and the body's normal response is to antagonize it with norepinephrine so the body doesn't kill itself on the adrenaline. That's the normal process. People with POTS create WAY too much norepinephrine and lead to an adrenaline dump.
It's also why workouts make POTS patients feel far worse than before with a complete absence of an adrenaline/dopamine high.
Methylene Blue inhibits the NOS which puts a cap on the norepinephrine, or that's the theory anyway.
Include breathing exercises like the Wim Hoff method to improve oxygen blood flow and it may just be what is needed.
I'm starting on a low dose of Methylene Blue, and I had to get off my SNRI because Methylene Blue works similar to St. John's Wort and can lead to serotonin syndrome which can kill.
If you do decide to take it, ONLY take pharmaceutical grade. There might be mercury in lab and fish-tank grades.
Take it under the tongue - only 15% gets in through the stomach.
4 drops of this brand is appropriate for a 200lb person. I'm only taking 1 at the moment.
Oh, and keep a toothbrush nearby in case it gets on your teeth. It is a clothes dye after all.
One last thing, I put it on a butterknife, dry the bottom of my tongue and then apply. It's the only way I have found to avoid getting it everywhere.
Mine did not come with a dropper...
Oh, I need to mention something important if you have the same problem I do.
Methylene Blue might be the proper treatment.
The active mechanism is as a NO -> NOS inhibitor.
POTS people don't have too much NO or NOS, but the creation of NOS is needed for spikes of norepinephrine.
Spikes of norepinephrine are pronounced in people with POTS, which is why many complain that caffeine makes them sleepy (it does for me).
The caffeine spikes adrenaline and the body's normal response is to antagonize it with norepinephrine so the body doesn't kill itself on the adrenaline. That's the normal process. People with POTS create WAY too much norepinephrine and lead to an adrenaline dump.
It's also why workouts make POTS patients feel far worse than before with a complete absence of an adrenaline/dopamine high.
Methylene Blue inhibits the NOS which puts a cap on the epinephrine, or that's the theory anyway.
Include breathing exercises like the Wim Hoff method to improve oxygen blood flow and it may just be what is needed.
I'm starting on a low dose of Methylene Blue, and I had to get off my SNRI because Methylene Blue works similar to St. John's Wort and can lead to serotonin syndrome which can kill.
If you do decide to take it, ONLY take pharmaceutical grade. There might be mercury in lab and fish-tank grades.
Take it under the tongue - only 15% gets in through the stomach.
4 drops of this brand is appropriate for a 200lb person. I'm only taking 1 at the moment.
Oh, and keep a toothbrush nearby in case it gets on your teeth. It is a clothes dye after all.