NOTE: NOT a doctor/vet/anything like that. Just digging.
- The first paper he links gives anti-Ivermectin arguments I've already heard
- "Occasional" adverse events (from what I've researched personally, very rare)
- Some of the first studies for Ivermectin vs. Covid-19 were done in vitro (in a culture dish and thus he's claiming not representative of real treatments)
My rebuttal to #1: I've heard the in-vitro argument before but we've seen the studies where where they're used in humans. To be fair, he goes on to note that these "don't follow proper reporting guidelines", but I'd need to dig further.
- He's mentioning harmful effects in humans with the mdr-1 gene mutation. As a background, certain dog breeds such as Collies that also have this gene can experience neurological effects in doses larger than (I believe) 600 micrograms/kg. I believe the human dose is 0.2mg/kg which is 200 micrograms/kg. However in the study I'm about to link this (does) in RARE cases cause issues like any other drug can.
I found a study on the neurological side effects of Ivermectin:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929173/
"The mechanism of these events has been debated in the literature, largely focusing on the role of concomitant high burden infection with L. loa versus the presence of mdr-1 gene variants in humans allowing ivermectin penetration into the central nervous system (CNS)."
So it's debated whether mdr1 is the issue or whether L. loa causes this. The author of this study claims that a patient's smeared blood stain didn't show evidence of microfilariae, which apparently discredits the possibility of a high density of L. loa being present. Thus the author of the study became concerned with Ivermectin itself.
However, it goes on to note that such events are rare:
"By comparison with the extensive post marketing experience with ivermectin in the successful treatment of parasitic infections, the number of reported cases suggests that such events are likely rare. However, elucidation of individual-level risk factors could contribute to therapeutic decisions that can minimize harms. Further investigation into the potential for drug–drug interactions and explorations of polymorphisms in the mdr-1 gene are recommended."
I've heard much good about this being used to treat Covid in the US.
3.) This Kats guy himself- his language seems to be that of a Liberal. "sorry, but no" along with saying that "early bootlegged manipulated studies don't count" and that Ivermectin "never demonstrated any efficacy". He also goes on to say the same about vitamin D, zinc, and Quercetin. (Dr. Zelenko uses these IIRC). He then goes on to tag the facebook profiles for the CDC and the NIH as though they're his allies and are going to help him, even though most on this site would agree that these organizations are corrupt.
Finally, despite his criticisms of pro-Ivermectin studies, he does not have that many studies to offer; his website links a few studies that talk about the use of melatonin as an anti-inflammatory and hypothetically call for its use for Covid-19 (but show no studies on actual patients), and then he links a paper describing how Niacin might hypothetically be used to treat Covid-19- authored by himself. The only other proof on his website is a screenshot of a few twitter posts thanking him.
Conclusion: I have tried to look at this honestly and "entertain a thought without accepting it" as Aristotle would say. I don't want to be biased- I'll admit I have been very pro-Ivermectin, but I just don't agree that the FLCCC is committing "crimes against humanity" and that it would be Fauci and the NIH to swoop in and save the day. If there are better ways, why aren't the NIH and the CDC pursuing them if they're on the up-and-up, as Kats makes it seem? Moreover, it seems that he is exaggerating rare Ivermectin side effects (even the author of such papers acknowledge they are rare). And finally, he needs to provide more, real evidence that HIS cure is better- it's currently not even up to par with the Ivermectin studies that he criticizes.
Again, not a doctor. If you have another opinion feel free to reply.