For GI upset take as little as what won’t cause that. Like 1/10th of the pill and raise every two weeks until side effect goes away.

You can also, ahem, use Metformin as a suppository and yes it’s fine to take that way all meds can be given rectally. It absorbs way faster but this is only for supplements as anyone’s regular medication needs to be for sure regulated strictly.

In that case it might come right out but it works like a charm, lol. Once your gut is empty you can try again but I do so at night and add a little water. Yep I’m stubborn!

We know about rectal routes in medicine in nursing because they used that route a lot before there were more meds to try, because people would get an upset stomach.

For GI upset take as little as what won’t cause that. Like 1/10th of the pill and raise every two weeks until side effect goes away.

You can also, ahem, use Metformin as a suppository and yes it’s fine to take that way all meds can be given rectally. It absorbs way faster but this is only for supplements as anyone’s regular medication needs to be for sure regulated strictly.

In that case it might come right out but it works like a charm, lol.