Summary
Through molecular analysis, the researchers found that the spike protein caused various changes in the brain and surrounding tissues, including an upregulation of pro-inflammatory proteins and proteins associated with blood clots.
These findings, the authors note, could help explain why some COVID-19 patients develop mini-infarcts (small areas of dead tissue due to lack of blood) and micro-bleeds in the brain.
they also found that the spike protein was linked to the disruption of proteins in the PI3K-AKT pathway, which is important in cell survival and growth.
Lastly, the study suggested a mechanism for the virus's entry into the central nervous system, hypothesizing that the spike protein first reaches the skull marrow and then the meninges before infiltrating the brain
https://www.twc.health/blogs/news/new-study-explores-effects-of-spike-on-brains-of-covid-19-patients
Summary
Through molecular analysis, the researchers found that the spike protein caused various changes in the brain and surrounding tissues, including an upregulation of pro-inflammatory proteins and proteins associated with blood clots.
they also found that the spike protein was linked to the disruption of proteins in the PI3K-AKT pathway, which is important in cell survival and growth.
Lastly, the study suggested a mechanism for the virus's entry into the central nervous system, hypothesizing that the spike protein first reaches the skull marrow and then the meninges before infiltrating the brain
https://www.twc.health/blogs/news/new-study-explores-effects-of-spike-on-brains-of-covid-19-patients