I haven't seen much posted about any clinical studies for using Remdesivir for Covid, specifically. Since it is the "standard of care" in most hospitals (due to demands from NIH), we should know if there is any SCIENCE to back up these mandates.
I found a couple of interesting studies.
(1) This one used Remdesivir in one group and placebo in another group. The only real analysis was how long it took the patient to get out of the hospital or moved out of the Covid wing of the hospital to another area of the hospital. This is subjective, to say the least.
The only real difference was the group who got the drug were "cleared" in 10 days, and the group who got nothing were "cleared" in 15 days.
They then went on to do a COMPUTER MODEL to claim that Remdesivir would "likely" lead to better outcomes regarding recovery and avoiding death. But they have no evidence of this. It's just a computer model.
https://www.nejm.org/doi/full/10.1056/NEJMoa2007764
(2) This one is a review of multiple studies for Remdesivir, and then they arrived at conclusions based on what they saw overall in the group of studies.
Based on the currently available evidence, we are moderately certain that remdesivir probably has little or no effect on all-cause mortality at up to day 28 in hospitalised adults with SARS-CoV-2 infection. [This means: It does NOT prevent people from dying.]
We are uncertain about the effects of remdesivir on clinical improvement and worsening. [This means that the review of MULTIPLE studies show NO benefit.]
There were insufficient data available to validly examine the effect of remdesivir on mortality in subgroups depending on the extent of respiratory support at baseline. [This means that not enough evidence exists to determine if Remdesivir is either safe or effective for "sub-groups" (elderly, children, pregnant women).]
Bottom line: Remdesivir is NOT proven effective in providing ANY benefit to SARS-CoV-2/Covid 19 patients.
Science!
I haven't seen much posted about any clinical studies for using Remdesivir for Covid, specifically. Since it is the "standard of care" in most hospitals (due to demands from NIH), we should know if there is any SCIENCE to back up these mandates.
I found a couple of interesting studies.
(1) This one used Remdesivir in one group and placebo in another group. The only real analysis was how long it took the patient to get out of the hospital or moved out of the Covid wing of the hospital to another area of the hospital. This is subjective, to say the least.
The only real difference was the group who got the drug were "cleared" in 10 days, and the group who got nothing were "cleared" in 15 days.
They then went on to do a COMPUTER MODEL to claim that Remdesivir would "likely" lead to better outcomes regarding recovery and avoiding death. But they have no evidence of this. It's just a computer model.
https://www.nejm.org/doi/full/10.1056/NEJMoa2007764
(2) This one is a review of multiple studies for Remdesivir, and then they arrived at conclusions based on what they saw overall in the group of studies.
Based on the currently available evidence, we are moderately certain that remdesivir probably has little or no effect on all-cause mortality at up to day 28 in hospitalised adults with SARS-CoV-2 infection. [This means: It does NOT prevent people from dying.]
We are uncertain about the effects of remdesivir on clinical improvement and worsening. [This means that the review of MULTIPLE studies show NO benefit.]
There were insufficient data available to validly examine the effect of remdesivir on mortality in subgroups depending on the extent of respiratory support at baseline. [This means that not enough evidence exists to determine if Remdesivir is either safe or effective for "sub-groups" (elderly, children, pregnant women).]
Bottom line: Remdesivir is NOT proven effective in providing ANY benefit to SARS-CoV-2/Covid 19 patients.
Science!
https://pubmed.ncbi.nlm.nih.gov/34350582/
We should start asking:
- Where is the FDA approval letter for Remdesivir use on Covid patients? (It might exist, but I doubt it.)
- Where are the Phase I, Phase II, Phase III studies showing that Remdesivir is safe and effective against SARS-CoV-2 (Phase III should be a 2-5 year clinical trial)?
- Where is the FDA Emergency Use Authorization for using Remdesivir for Covid 19 patients?
They claim there is no evidence for using Ivermectin successfully on Covid (even though there is), so the standard of care for Covid is Remdesivir. OK, so where is the evidence for using Remdesivir?
If I am right about this, then hospitals will NOT be able to answer this question. They are using a drug as "standard of care" that is KNOWN to be FATAL in other uses, while having ZERO PROOF that it is actually effective in Covid patients.
How can they justify using an UNPROVEN drug that is KNOWN TO BE FATAL for patients with virus (ebola) as their "standard of care," but refuse treatments that have proven to be effective against Covid (HCQ, Ivermectin)?
"Just following orders" is NOT an answer to the question.
I would bet that they don't have an answer. Many of them might not have even thought to ask!