I wonder that, too. I have a friend with Lupus; she had been in 'remission' while on HCQ. When her rheumatologist retired, and she was handed over to a new one, the new doc ran all the diagnostic tests on her, and told her she didn't have Lupus. Duh! Because it was controlled with HCQ! He took her off of the drug, and she has gone down hill since. She is not the same lovely person on the outside, and her insides are deteriorating. I am so angry at stupid doctors on her behalf.