Dr Judy :
https://wearethene.ws/notable/220526
Anon finds references for Suamin and Autism
- Suramin and Autism Suramin is a 100-year-old drug developed to treat African sleeping sickness and river blindness. Though it has been investigated for other diseases, including cancer, it is not approved for any therapeutic use in the United States. However, a small, randomized clinical trial conducted by Robert Naviaux, MD, PhD , professor of medicine, pediatrics and pathology, and colleagues at University of California San Diego School of Medicine have found that a single intravenous dose of suramin produced dramatic, but transient, improvement of core symptoms of autism spectrum disorder (ASD). Currently, there are no drugs approved for treating the core symptoms of ASD.
More broadly, the trial findings support the “cell danger response theory,” which posits that autism and other chronic conditions are fundamentally driven by metabolic dysfunction—and thus treatable. Naviaux and his co-authors propose larger, longer clinical trials to assess suramin (or similar drugs) as an ASD treatment. …
https://health.ucsd.edu/news/topics/suramin-autism/pages/default.aspx
- '''Autism and Suramin in the Time of COVID-19' May 13, 2020 — Autism spectrum disorder (ASD) is a complicated condition with multiple causal factors. At the most basic level, we believe ASD is the result of a multisystem cellular response to environmental and genetic stresses. Called the cell danger response, it results in over-release of ATP, the fundamental carrier of energy. Too much ATP signaling disrupts normal functioning in many types of cells, including how neurons communicate and work together.
Suramin is a century-old drug used to treat African sleeping sickness or trypanosomiasis. It works by inhibiting ATP signaling. In animal studies and in a small Phase I/II clinical trial completed in 2017, we reported that suramin produced dramatic reductions in classic ASD symptoms, such as social abnormalities and learning disabilities. These improvements were temporary, and disappeared in about 8 weeks after the single dose of suramin wore off. We are now in development of a second, larger clinical trial. Progress toward this trial has been slow but steady, no surprise given the complexity of ASD and the need to advance this novel approach carefully, fully supported by empirical evidence and best scientific practices.
Like labs around the world, we have not been immune from the effects of the SARS-CoV-2 pandemic. It has caused some delays and complications. Nonetheless, we expect to have all approvals in place to launch the second trial in spring of 2021.''
https://health.ucsd.edu/news/topics/Suramin-Autism/Pages/COVID-19-Response.aspx https://archive.is/wip/6i9KE
- Updates at Dr. Naviaux website https://naviauxlab.ucsd.edu/
I am old and was never diagnosed with anything. They apparently didn't know about Asperger's or ADHD way back in the 50s and 60s.
Your daughter has skills, and I think she needs to be allowed to develop them. Not everyone needs everything that regular school offers. Perhaps when she's older, you can find an employer willing to allow her to do what she's best at by herself without interference.
I wish I'd had less interference at my last job. That's why I finally quit at the age of 50. I've been retired and sitting in my room by myself most of the time since then. I'm very happy now.
If she's happy, just keep others away and let her find her own way.
I don't play well with others either. They are confusing, waste far too much time, never say what they mean. Indeed, shortly I will be taking my daughter on three days a week on her own and every weekend with her sister here at my place. I'm the only one who understands her and people are finally realizing that.