Absolutely. I certainly don't believe that all human attributes are unchangeable. The "feel stupid become stupid" one is a good example.

I'll even grant that some behaviors that most see as being part of one's "gender" are shaped by social influences --certain customs and attitudes. And that sexuality is based partially on innate predisposition but also shaped in early childhood (=psychological factors, environment, etc.).

But the idea that we can (or should) change all aspects of ourselves might be based somewhat on the fact that we aren't grateful for what we are given as you say.