They gave patients 2,400mg in the first day of treatment, instead of the recommended 200-400mg. Doses over 1500mg are associated with fatality, so patients received a potentially lethal dose.
Pure evil.
Edit: Corrected figures. I originally referenced a news report I watched regarding a specific hospital in the UK (which gave doses even more lethal than the official recommended deadly doses). From the linked article, it wasn't just a one off hospital making a mistake. Many hospitals across the UK were instructed to give dangerously high doses of hydroxychloroquine.
No it does not. It is still in the lethal dose range. The danger of giving too much HCQ in a loading dose is because of its pharmacokinetic profile. It has a plasma half life of 123 days. This means that the drug is incredibly slow to clear the body. Anyone setting a dose of this drug should know that however. The regimen that was recommended just kept packing the system with more (unneeded) drug.
Should be up on charges. But this dose SHOULD have been noticed by the many Docs and Pharmacists dispensing it. Crazy bad practice. Seems unbelievable.
This happened in the UK.
They gave patients 2,400mg in the first day of treatment, instead of the recommended 200-400mg. Doses over 1500mg are associated with fatality, so patients received a potentially lethal dose.
Pure evil.
Edit: Corrected figures. I originally referenced a news report I watched regarding a specific hospital in the UK (which gave doses even more lethal than the official recommended deadly doses). From the linked article, it wasn't just a one off hospital making a mistake. Many hospitals across the UK were instructed to give dangerously high doses of hydroxychloroquine.
Your math is waaaaaaaaaaaaaaay off. Read the article again.
Your right it was only 4 times the normal dosage and 2 x the lethal dose. That makes it ok
No it does not. It is still in the lethal dose range. The danger of giving too much HCQ in a loading dose is because of its pharmacokinetic profile. It has a plasma half life of 123 days. This means that the drug is incredibly slow to clear the body. Anyone setting a dose of this drug should know that however. The regimen that was recommended just kept packing the system with more (unneeded) drug. Should be up on charges. But this dose SHOULD have been noticed by the many Docs and Pharmacists dispensing it. Crazy bad practice. Seems unbelievable.
what I said was sarcasm for the above response......
Thanks. I've corrected my figures.