No, of course mRNA doesn't turn into DNA, where did you get that from? The question is if this synthesized mRNA can be reserve-trascribed into cDNA and integrated into the genome which would forever alter it and would be passed on genetically. This pubmed article is behind a paywall, if anyone has full access, please post:
To experimentally corroborate the possibility of viral retro-integration, we describe evidence that SARS-CoV-2 RNAs can be reverse transcribed in human cells by reverse transcriptase (RT) from LINE-1 elements or by HIV-1 RT, and that these DNA sequences can be integrated into the cell genome and subsequently be transcribed.
No, of course mRNA doesn't turn into DNA, where did you get that from? The question is if this synthesized mRNA can be reserve-trascribed into cDNA and integrated into the genome which would forever alter it and would be passed on genetically. This pubmed article is behind a paywall, if anyone has full access, please post:
https://pubmed.ncbi.nlm.nih.gov/33330870/
To experimentally corroborate the possibility of viral retro-integration, we describe evidence that SARS-CoV-2 RNAs can be reverse transcribed in human cells by reverse transcriptase (RT) from LINE-1 elements or by HIV-1 RT, and that these DNA sequences can be integrated into the cell genome and subsequently be transcribed.