-Pfizer's the first vaccine on the market. 3 weeks later Moderna is on the scene, then within a month or so, J&J pops in with the single dose vaccine.
-Clinically, we have three treatment options. The Pfizer and Moderna are 2-dose vaccines, but the Pfizer's a pain in the butt because it has to be stored in deep freeze or on dry ice and no corner pharmacy has a deep freezer. J&J's a single dose and it can be stored in the refrigerator. It's slightly less effective at 70% vs 95% and 94%, but it's also one shot and easy to distribute.
-That means J&J's your first choice for anyone without a ton of comorbidities, followed by the Moderna, and Pfizer last because of the supply chain issues.
-Astra Zeneca also has a vaccine that's widely used all over the world outside of the US, but hasn't been approved here because FDA claims it was causing blood clots in the EU and wanted more data in the elderly (despite having real world data from literally millions of Europeans who've already had it).
So, FDA steps in:
-Astra Zeneca's NDA was denied. No EUA for them. They're too late to the table and FDA basically blocked them by demanding multiple new phase 3 clinical trials that'll require at least a year or more to complete, even with interim data. They're out of the game.
-Then J&J (the first choice) ends up having a factory shut down in Baltimore because of contamination. Keep in mind it was shut down... in a chocolate city. Normally, they'd just tell J&J to clean up the place, block the effected lots, and let them get back to work after passing a new inspection, and especially they'd do that to avoid having to deal with the bad PR of being called "rayciss." That set back J&J, but people still liked the single shot and they were manufacturing out of other plants just fine.
-Then we start hearing about myocarditis and it initially gets attached to J&J's vax. FDA slaps a warning label on it and lets fear take over. Now, no doctor is willing to recommend it, and just like that, FDA just took out the #1 option.
-Then a few weeks later, Moderna's vax starts getting associated with myocarditis and now it gets the warning label as well. Boom, #2 gone.
-Lastly, NovaVax has a traditional protein vaccine that many healthcare workers were waiting for so they could avoid the mRNA and adenovirus-delivered shots, but it's being slow walked by the FDA and progress has effectively stalled.
Meanwhile:
-Pfizer has now effectively had the FDA clear out it's competition
-Pfizer has now had the FDA kill any new treatments (HCQ, IVM, others)
-And Pfizer just posted something like $9 billion in Q2 2021 earnings, on track for $33 billion in revenue this year!
If you don't think the system's rigged at this point...
A little perspective for funsies:
-Pfizer's the first vaccine on the market. 3 weeks later Moderna is on the scene, then within a month or so, J&J pops in with the single dose vaccine.
-Clinically, we have three treatment options. The Pfizer and Moderna are 2-dose vaccines, but the Pfizer's a pain in the butt because it has to be stored in deep freeze or on dry ice and no corner pharmacy has a deep freezer. J&J's a single dose and it can be stored in the refrigerator. It's slightly less effective at 70% vs 95% and 94%, but it's also one shot and easy to distribute.
-That means J&J's your first choice for anyone without a ton of comorbidities, followed by the Moderna, and Pfizer last because of the supply chain issues.
-Astra Zeneca also has a vaccine that's widely used all over the world outside of the US, but hasn't been approved here because FDA claims it was causing blood clots in the EU and wanted more data in the elderly (despite having real world data from literally millions of Europeans who've already had it).
So, FDA steps in:
-Astra Zeneca's NDA was denied. No EUA for them. They're too late to the table and FDA basically blocked them by demanding multiple new phase 3 clinical trials that'll require at least a year or more to complete, even with interim data. They're out of the game.
-Then J&J (the first choice) ends up having a factory shut down in Baltimore because of contamination. Keep in mind it was shut down... in a chocolate city. Normally, they'd just tell J&J to clean up the place, block the effected lots, and let them get back to work after passing a new inspection, and especially they'd do that to avoid having to deal with the bad PR of being called "rayciss." That set back J&J, but people still liked the single shot and they were manufacturing out of other plants just fine.
-Then we start hearing about myocarditis and it initially gets attached to J&J's vax. FDA slaps a warning label on it and lets fear take over. Now, no doctor is willing to recommend it, and just like that, FDA just took out the #1 option.
-Then a few weeks later, Moderna's vax starts getting associated with myocarditis and now it gets the warning label as well. Boom, #2 gone.
-Lastly, NovaVax has a traditional protein vaccine that many healthcare workers were waiting for so they could avoid the mRNA and adenovirus-delivered shots, but it's being slow walked by the FDA and progress has effectively stalled.
Meanwhile:
-Pfizer has now effectively had the FDA clear out it's competition
-Pfizer has now had the FDA kill any new treatments (HCQ, IVM, others)
-And Pfizer just posted something like $9 billion in Q2 2021 earnings, on track for $33 billion in revenue this year!
If you don't think the system's rigged at this point...