“ The substitution of Lys (K) to Arg (R) at positions 211 and 341 was shown to increase the electrostatic attraction between SARS-CoV-2 and ACE2 by 1.29-fold and 1.47-fold in comparison to the WT”
The Lysine to Arginine switch is how biologists deducted this was homegrown: you don’t see this codon switch in nature. But you CAN buy it in a viral vector insertion kit for the protein furinase on Thermo Fisher’s website.
“ The substitution of Lys (K) to Arg (R) at positions 211 and 341 was shown to increase the electrostatic attraction between SARS-CoV-2 and ACE2 by 1.29-fold and 1.47-fold in comparison to the WT”
The Lysine to Arginine switch is how biologists deducted this was homegrown: you don’t see this codon switch in nature. But you CAN buy it in a viral vector insertion kit for the protein furinase on Thermo Fisher’s website.