"COMIRNATY includes the presence of optimized codons to improve gene expression."
analysis showed two codons -- one coding for proline in the spike, to make it hold up better, not collapse, the other helped the antigens evade immune system detection for longer (similar to HIV) so as to build up a greater 'dose' of spike proteins before your own antibodies mount a resistance.
the difference, according the the FDA:
analysis showed two codons -- one coding for proline in the spike, to make it hold up better, not collapse, the other helped the antigens evade immune system detection for longer (similar to HIV) so as to build up a greater 'dose' of spike proteins before your own antibodies mount a resistance.