It looks like she got fat. The hands are one of the more difficult things to fix to appear more youthful, adrenochrome or not. I'll never understand the stupidity of the beauty industry though. People want to look young when they're not young but then again most people are afraid of getting old and dying and look for anything they can find to make themselves feel better about that reality that they refuse to face.

Some use cosmetics, some pray to a god in hopes of magically living forever after death, some choose the worst possible route being adrenochrome but it all boils down to people being afraid of getting old because the older the we simply means the sooner we're likely to die. Death is a part of life, getting old is a part of life, people should learn to embrace that.

Now for Madonna and those involved with adrenochrome, well they partly do it because they believe they'll live longer but they're also doing it as part of their worship to their own god they believe in. If people would just accept realities of life that us mere humans cannot change then more people would be able to live much happier lives.