"Here’s the irony: some of the preexisting conditions that make a COVID infection especially dangerous – such as high blood pressure, diabetes, heart failure and arrythmias – often are treated with multiple medicines that could also make Paxlovid dangerous.
Some of the common cardiac medications that you cannot take with Paxlovid include amiodarone, flecainide, Plavix, Brelinta and some statins. Some of these can be stopped for the 5-day course of Pavlovid. But other meds, like amiodarone, hang around in the body for quite a while, and adding Paxlovid is completely contraindicated.
Paxlovid is a combination drug (nirmatrelvirvco-packaged with ritonavir). It inhibits an enzyme in the body essential to produce cholesterol, steroids, and prostacyclins, and can increase the concentration of many other medications
What’s more, many people might not even realize that they could be harmed by this new medication. Since at least 40% of American adults, are considered obese, 14% smoke, and over 10% have diabetes, there are a lot of people at high risk even though they may feel well. They are all potential candidates to develop severe COVID, may need therapy, and an unknown number are taking multiple medications that can interact with Paxlovid."
Here's the archive of the Ink article and a clip:
https://archive.ph/CmXkL#selection-611.0-645.106
"Here’s the irony: some of the preexisting conditions that make a COVID infection especially dangerous – such as high blood pressure, diabetes, heart failure and arrythmias – often are treated with multiple medicines that could also make Paxlovid dangerous.
Some of the common cardiac medications that you cannot take with Paxlovid include amiodarone, flecainide, Plavix, Brelinta and some statins. Some of these can be stopped for the 5-day course of Pavlovid. But other meds, like amiodarone, hang around in the body for quite a while, and adding Paxlovid is completely contraindicated.
Paxlovid is a combination drug (nirmatrelvirvco-packaged with ritonavir). It inhibits an enzyme in the body essential to produce cholesterol, steroids, and prostacyclins, and can increase the concentration of many other medications
What’s more, many people might not even realize that they could be harmed by this new medication. Since at least 40% of American adults, are considered obese, 14% smoke, and over 10% have diabetes, there are a lot of people at high risk even though they may feel well. They are all potential candidates to develop severe COVID, may need therapy, and an unknown number are taking multiple medications that can interact with Paxlovid."