I had a real bad reaction to Depakote while hospitalized for manic depression .... went to sleep and woke up 4 days later. was told I was waking up eating and falling back to sleep but have no memory. when they took me off it I was awake for 5 days on a manic high. in the end was hospitalized for a month while they tried to stabilize me on medications. never stabilized suspect the reason I was released was insurance ran out. never got stability till stopped getting into stressful situations and the meds were out of my system for 3 years.