The Euphrates is a similar situation. Water is diverted from the to provide water for major cities in Iraq.

If you end up hearing about the Colorado river being low, again, diversion to cities for drinking water and human uses. The Rio Grande is seeing the same things in sections down-river from major points where the water flows are diverted.

These are human-caused problems, generally speaking, from poor water management and some dubious overuse issues, especially in desert regions.