For a preemptive header, this is the original document describing the study done by Boston University. I've been seeing the news lately pushed about the research on Omicron and OG WuFlu done on mice, and having dug into the research done, there's several issues to be had with it.

1: Small sample sizes, the Boston researchers admit in their testing that they only have 6 mice tested for the original Wuhan strain, and 10 for their "Chimera" Omicron-Wuhan strain. Small sample sizes are highly suspect for statistical claims, given the overt possibility of over-representing hazards that may not be present in a broad studied population.

2: Using humanized mice engineered to be at risk of Corona. The researchers also admit that they are using K18-hACE2 mice. These mice are genetically engineered to specifically be at extreme risk of normal Coronavirus infections, with some labs claiming they are "reaching criteria for euthanasia ~5-8 days post-challenge" after Coronavirus inoculation. We can see this at play when they quote numbers for the original Wuhan strain tested on the 6 mice, which is 100% fatality rate. 100% fatality rate is so utterly out of line with even the hyper-exaggerated official deaths for Coronavirus that it would call into question their 80% number for the "Chimera" Omicron-Wuhan strain they cooked up.

3: All the numbers they claim don't even match the original Wuhan strain, not viral load, "The plaque assay showed that although both Omi-S and Omicron produced lower levels of infectious virus particles compared with WT", not infectivity, "WT SARS-CoV-2 produced the highest levels of infectious virus particles", nor lethality "WT and Omi-S caused mortality rates of 100% (6/6) and 80% (8/10)". The gain of function can't even be called that, it's barely restoration of function, the bare minimum that the Wuflu originally had.

None of this excuses their clear goal of gain of function, but if this is what they want to release, they need to try harder.