there have certainly been attempts here and there. but humanity wasn't organized enough to make a cohesive effort. the enemy is a subversive nd relatively small group that has been able to go undetected and gain the upper hand in many ways. they have been prevented from accomplishing their primary objectives, which were either a) escape, b) domination, or c) destruction, in order of their preference.

the internet allowed humanity to organize enough to flip the balance in our favour, which is why we've seen them put so much effort into controlling the flow of information online. when it was clear that wasn't enough, they attempted covid lockdowns, which was a domination endgame card that they were forced to play too early, and it only served to solidify humanity's resolve and tip the balance even further in our favour. they will try it again, but at this point they would be just as happy to nuke the whole place... if they can't have it, nobody can. at least, that's their wishful thinking. but the plan is now in play, and all three of their main objectives are impossible. anything we see from them now are just death throes while the ending plays out, and humanity is made ready for the end of quarantine. hence the movie.