Not necessarily, you can't use rodents and or even monkeys to model everything in the human body as just because we have a lot of shared DNA doesn't mean that their immune systems and such are as complex as ours. There's many many cases of testing molecules that had a desired effect in an animal but once in a human it doesn't act the same way, which is why there are medications that are used in both humans and pets but some of them have the opposite intended or side effects (like one that I've used to treat insulinoma in ferrets, it causes ferrets to regrow their hair but in humans their hair falls out.) Even studies done on the petri dish with human cells don't work the same way as in the body as the petri dish is missing all of the other interactions that could cancel out the desired effect.
They would have found this out during the animal studies.
Not necessarily, you can't use rodents and or even monkeys to model everything in the human body as just because we have a lot of shared DNA doesn't mean that their immune systems and such are as complex as ours. There's many many cases of testing molecules that had a desired effect in an animal but once in a human it doesn't act the same way, which is why there are medications that are used in both humans and pets but some of them have the opposite intended or side effects (like one that I've used to treat insulinoma in ferrets, it causes ferrets to regrow their hair but in humans their hair falls out.) Even studies done on the petri dish with human cells don't work the same way as in the body as the petri dish is missing all of the other interactions that could cancel out the desired effect.
Yes, true. Pharmaceuticals can work differently between species. Different immune systems, too. It's complicated. And so interesting.