No,I was saying you need to diagnose it before you go cutting it out so that you know what kind of margins one needs to make around the lesion. If is it malignant you will likely be removing that area anyway. So if you have a large lesion on the skin an incisional biopsy is required. If you have a deep lesion a needle biopsy seems in order. If the lesion is in bone and is large a biopsy must be done so you would know weather to curette the lesion out or do a wide resection of bone that would also require reconstruction (plating, bone grafts, etc.). You don't just go in willy nilly as if you have microscopic eyes and know what you are removing. You can guess but that is not very accurate and may be irresponsible leading to malpractice. Sometimes frozen sections are indicated when doing a wide resection and you're looking for clean margins in a hospital setting. Most lesions are biopsied in the office to determine their nature. If non malignant a simple excision can be done in the office if not of considerable size. If malignant then a partial lip removal, or wide excision would be done in the hospital, likely with frozen sections. This must be scheduled also with the in hospital pathologist so that he/she is prepared for the procedure. Personally I wouldn't mess with an adenocarcinoma, I would be sure to get it all. I practiced 30 years as an Oral & Maxillofacial Surgeon and kept up with all the latest recommendations and standards of care, operating both in office and in hospital settings. I hope I knew what I was doing all those years. Never lost a patient and never got sued.