What I understand, the brain cells don't commit apoptosis and regenerate, so the spike proteins wouldn't be developing there, correct? There's somewhere else in the body that doesn't go thru this as well - I just can't find it right now.
Spez: Nerve cells and Cardiovascular cells don't go through apoptosis along with brain cells.
Prions spread by one misfolded protein causing the next one to misfold by contact, then the body replaces the original protein giving more protein stock to misfold . I think it happens in glial cells rather than neurons. The idea is that the spike proteins cause the original misfolds and start the prion cascade. I don't think just few spike protein molecules which have somehow come from the environment and made it through the blood brain barrier will be enough to start that cascade.
What I understand, the brain cells don't commit apoptosis and regenerate, so the spike proteins wouldn't be developing there, correct? There's somewhere else in the body that doesn't go thru this as well - I just can't find it right now.
Spez: Nerve cells and Cardiovascular cells don't go through apoptosis along with brain cells.
Prions spread by one misfolded protein causing the next one to misfold by contact, then the body replaces the original protein giving more protein stock to misfold . I think it happens in glial cells rather than neurons. The idea is that the spike proteins cause the original misfolds and start the prion cascade. I don't think just few spike protein molecules which have somehow come from the environment and made it through the blood brain barrier will be enough to start that cascade.