Bioavailability of ivermectin is more 2x more effective with food. Quercetin is what makes zinc bioavailable, as well as acts as a rudimentary replacement of hcq. All three can cause stomach issues, though my horse hasn't had any problems, his Filly did experience some stomach discomfort. Both horses were back to normal in 72 hours. I'm not a veterinarian though, so I would recommend doing a little research. It is wise usually to take any supplements with food to avoid stomach upset. I was reading a few older posts here that explains zinc should be taken with copper as it depletes copper to be absorbed. Quercetin acts as a carrier for both. I added: Echinacea 380mg 2x daily Arnica oral tablets, as directed on the bottle for body ache. Lysine 2000mg Rhidolia Rosea 375mg 2x daily (ultra adaptogen and quite fascinating stuff.) Vitamin C 1000mg 2x daily Tylenol 500mg 2x daily since my Filly had a bit of a fever.

My horses were taking the durvet ivermectin for 5 days and then stopped. One tube treated both horses.. Both are back to complete health, although my horses seem to still be unable to smell or taste much of anything, it is returning slowly. Again, I'm just a veteran country lad, not a veternarian. Be sure to weigh your horses and calculate accordingly. Hope this helps.