Poly(ethylene glycol) (PEG) is a hydrophilic oligomer consisted of low molecular weight of polyether compound generally synthesized from ethylene oxide. PEG is consisted of a repeating unit of ethylene glycol, –(O–CH2–CH2)–. PEG is prepared via polycondensation reaction of ethylene glycol compound in the presence of acidic or basic catalysts, produced a lower molecular weight product.
What is ethylene oxide?
At room temperature, ethylene oxide is a flammable colorless gas with a sweet odor. It is used primarily to produce other chemicals, including antifreeze. In smaller amounts, ethylene oxide is used as a pesticide and a sterilizing agent. The ability of ethylene oxide to damage DNA makes it an effective sterilizing agent but also accounts for its cancer-causing activity.
PEGs potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[46] Ethylene glycol and its ethers are nephrotoxic if applied to damaged skin.[47
Poly(ethylene glycol) (PEG) is a hydrophilic oligomer consisted of low molecular weight of polyether compound generally synthesized from ethylene oxide. PEG is consisted of a repeating unit of ethylene glycol, –(O–CH2–CH2)–. PEG is prepared via polycondensation reaction of ethylene glycol compound in the presence of acidic or basic catalysts, produced a lower molecular weight product.
What is ethylene oxide? At room temperature, ethylene oxide is a flammable colorless gas with a sweet odor. It is used primarily to produce other chemicals, including antifreeze. In smaller amounts, ethylene oxide is used as a pesticide and a sterilizing agent. The ability of ethylene oxide to damage DNA makes it an effective sterilizing agent but also accounts for its cancer-causing activity.
PEGs potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[46] Ethylene glycol and its ethers are nephrotoxic if applied to damaged skin.[47