My mom got the J&J in late winter. Approximately 2 months later she felt "crummy"; she had no energy, felt nauseated, brain fog, would forget her train of thought mid-sentence...My mom is low energy to begin with(adrenal issues in my opinion), but this was still a change that I could observe as well. I gave her pine needle tea. She drank that every other day for about a month. She now takes Vitamin D, zinc, quercetin, Vitamin C, and N A C. She has improved.