Here’s an interesting article about it:

https://ancientpatriarchs.wordpress.com/2017/02/04/giants-humans-with-six-fingers-six-toes/

The Bible references giants with 6 fingers and 6 toes (Nephilim).

1 Chronicles 20:6 (NASB) Again there was war at Gath, where there was a man of great stature who had twenty-four fingers and toes, six fingers on each hand and six toes on each foot; and he also was descended from the giants.