Just to build more upon the process a little, researchers will use 3rd generation sequencing techniques (oxford nanopore, illumina Hi-Fi, etc) on samples from say a cell culture exposed to a drug or patients in a study with a disease. Then, after cleaning it up by getting rid of low quality "reads," they "map" or "align" them to a reference genome. This provides a file with the sample DNA or RNA bits organized according to where they fit in the genome. Of course the samples will have variation but the location and by extension molecular components they interact with (histones) can be observed. This can be used to look at what genes interact with what.
A good example is cancer research. There you can identify that hey these people all have this type of breast cancer and they also have these features in their genome. While I dont agree with altering God's designed DNA, this research is useful for precision medicine where people can get the right drug for them based on their unique needs and medical interventions of that sort. And this doesnt rely upon transhumanism or gene therapy. If the whole damn industry wasn't so corrupt and aiming for gene alteration, we could really be helping people even more than what people realize.
Back to the post though, the previous reference genome is called GRch38 and that already had the gene rich regions mapped. Im not positive where the DNA came from because it jas been deidentified to protect the patients as is required for medical data. But I do know that it used a majority of white european descent people with current work aiming to expand it further into other races.
This CHM13 ref genome added 115 protein coding genes which is very small compared to the 23k or so genes in the genome already. But its improtant to note that this refernece genome isnt really and could not possibly be representative of the variation in such a large population as the white population in the west. It is basically just a consensus of the most common genes.
The alleles of a gene are the specific version an individual has and those are what I imagine nefarious actors would be collecting data on for weapons. They want to know what alleles of genes are basically only represented in the target pop. and theyd use that to make a virus or something to target only people with that feature. I wouldnt be surprised if that is what was going on in the labs in Ukraine.
Just to build more upon the process a little, researchers will use 3rd generation sequencing techniques (oxford nanopore, illumina Hi-Fi, etc) on samples from say a cell culture exposed to a drug or patients in a study with a disease. Then, after cleaning it up by getting rid of low quality "reads," they "map" or "align" them to a reference genome. This provides a file with the sample DNA or RNA bits organized according to where they fit in the genome. Of course the samples will have variation but the location and by extension molecular components they interact with (histones) can be observed. This can be used to look at what genes interact with what.
A good example is cancer research. There you can identify that hey these people all have this type of breast cancer and they also have these features in their genome. While I dont agree with altering God's designed DNA, this research is useful for precision medicine where people can get the right drug for them based on their unique needs and medical interventions of that sort. And this doesnt rely upon transhumanism or gene therapy. If the whole damn industry wasn't so corrupt and aiming for gene alteration, we could really be helping people even more than what people realize.
Back to the post though, the previous reference genome is called GRch38 and that already had the gene rich regions mapped. Im not positive where the DNA came from because it jas been deidentified to protect the patients as is required for medical data. But I do know that it used a majority of white european descent people with current work aiming to expand it further into other races.
This CHM13 ref genome added 115 protein coding genes which is very small compared to the 23k or so genes in the genome already. But its improtant to note that this refernece genome isnt really and could not possibly be representative of the variation in such a large population as the white population in the west. It is basically just a consensus of the most common genes.
The alleles of a gene are the specific version an individual has and those are what I imagine nefarious actors would be collecting data on for weapons. They want to know what alleles of genes are basically only represented in the target pop. and theyd use that to make a virus or something to target only people with that feature. I wouldnt be surprised if that is what was going on in the labs in Ukraine.