Actually its in Mesopotamian cultures around 4000bc which represents Ningishzida who represents plants and agriculture. His father Ninazu is also associated with snakes and is a god of the underworld.

I know this was a low-effort copy paste from you, but if you can provide me in detail what god you are referring to, I can then do study on this god and determine of this is true or not. But so for from what I see the earliest is agriculture which is intertwined woth commerce, expectially in the agrarian ages.