There are some conditions that are helped by the pharmaceuticals, when all else seems to fail. Have you ever had "The Mauve Test" for Pyroluria done on him? It's a simple urine test. Then the dosages of B6, Zinc, Omega 6 and Manganese can be adjusted to whatever his 'shedding' levels are. In Pyroluria, the person reacts to stress with a 'washout' of these nutrients which compounds the stress.. then more 'washout'... it's a downward spiral.

It is similar to what happens when a person is deficient in Vitamin C - as in when sailors out on the open sea for months were deprived of this nutrient got "Scurvy" which in it's final stages was insanity.

There are lots of forums that discuss Pyroluria out there and I found them to be very helpful. Good luck with your Son.