My favorite part of the article about why we should keep using antidepressants:
"Many commonly used medicines were used for decades before we understood their mechanisms of action: from aspirin to morphine to penicillin. Knowing they worked provided the impetus for establishing how they worked; and this knowledge generated new treatments."
Given that studies show that anti-depressants don't really work better than placebo, not as compelling argument as this statement would be for, IDK, Ivermectin?
Clown world. Links below.
I remember reading in the nineties that Prozac didn't outperform the placebos in its pre-release trial. It really isn't that much more effective than the older ones on the market, but the side effects are far more tolerable. This helped its popularity when it came out.
Several books on depression back then admitted that the "lack of serotonin" theory wasn't that much of an explanation. These weren't even medical tomes, just general audience paperbacks.