Before my mom died in 2016, she had lupus and she was on so many pills that all began with just her lupus medication. At one point, she was prescribed ambien, we didn't even know she was taking it. She was always so sick and I don't think it was just her lupus causing it. Nausea, diarrhea, constipation, dry throat, headaches, insomnia, it just goes on and on. When she was on her death bed, her doctor couldn't even understand what was wrong with her. Personally, I think it was a combination of lupus, not enough nutrients, the pills, and I think she just gave up mentally and her body followed suit.