I think orange is just a generic warning color, like on the street signs. This particular orange probably references the warning scene in Requiem for a Dream.

At the time, that was a warning about the Taliban shutting down the poppy fields, so somebody was gonna have to go there and take back the heroin production. I wonder who that was...

Anyhow, it appears it's being used again to warn about something promised -- DeSantis for President? -- that will be taken away abruptly, as in the movie.