Comfort basically. For example, most people tend to either carry on their hip, or their appendix. The hip is the go too for most people, but at the same time there IS a difference between male and female. It's much more common for men to wear loose and baggy clothing that's "breathable". Ergo, putting a gun on your hip is much more comfortable and ergonomic for a man since he has more leeway in his pants to make room for a gun.

Contrast this with women, who tend to wear more form fitting or "skintight" clothing. Not as much room anything with an actually concealed holster/gun.

Likewise, for those that choose appendix carry, women tend to have a bit of an advantage over men. Given it's location, women can more comfortably carry a gun and holster since they don't have to worry about their genitals like a man would.

Ever sit for a few hours with a 3 pound gun grinding into your groin because you wore pants that were just slightly too tight when you added the gun into your ensemble?

Yeah, not a fun time.

So yeah, gender does make a difference when making these considerations. It's why there are whole companies dedicated to gender specific conceal carry wear. I really don't know how it works, but there do exist yoga pants, leggings, skirts, etc. for women that have some form of sorcery cast on them to enable them to hide full size 1911 or glocks without it printing.

Blows my mind, but they exist.

Likewise, there's men's wear that's designed to take advantage of the "looser" styles that men tend to favor in order to basically carry around a small armory with you. (I've seen some coat, shirt, pants combos that basically let you carry enough guns and ammo to arm a small squad with a full size pistol and a couple hundred rounds each).

So yeah, gender is a factor in these things. It's not something people tend to think about, but the differences between men and women (even small differences like difference in dress styles), tends to result in unique patterns that make them different.