Rumors about Bin Laden being killed inside a cave right before the CNN interview so that he would not be able to make another one contradicting the narrative. But I am aware at some point Osama was rouge after the CIA did not back his attempt at removing the Saudi royal family from power.

Fidel Castro is another example of CIA asset gone rogue. He was an assassin and killed the Colombian president in Bogota in 1948 for the CIA. He was also helped during the 1950s rebellion that ended in 1959 with Fulgencio Batista leaving Cuba and Castro taking over the island. When Fidel had full control he decided to nationalize industry and thanks to the lobbying power of the millionaire and billionaire class that owned most of the industry on the island, Castro was made an enemy and the CIA quickly moved to assassinate him. Being a CIA assassin himself, he quickly dismantled any possible methods for infiltration by the CiA.. he even had his own intelligence agency the ministry of interior, infiltrate the Masonic lodges and different religious groups to cover all possible attacks or revolts.