Dont have any improvements to talk about.
But yesterday the bad breath drooling and licking are back. Not as bad as it has been.
She didnt eat last night.mainly laid on the couch sleeping with us. Its not uncommon for her to sleep all day,she was never a very active energetic dog. Its not uncommon for her to not eat at night plus she had a pretty big breakfast yesterday.
Yes. All meat.
GREAT!. make sure it is truly all he gets. No "treats"
This is how cancer grows and how to fight it.
Aerobic Glycolysis (Warburg Effect): In normal cells, glucose is metabolized through a process called aerobic respiration, which involves glycolysis followed by the citric acid cycle and oxidative phosphorylation in the mitochondria. However, cancer cells tend to favor glycolysis even in the presence of oxygen, leading to the production of lactate as a byproduct. This allows cancer cells to generate energy rapidly, support their high proliferation rates, and adapt to the microenvironment of tumors.
Lactate Fermentation: In addition to aerobic glycolysis, cancer cells may also rely on lactate fermentation. This involves the conversion of pyruvate, a product of glycolysis, into lactate. This process helps regenerate the cofactor NAD+ (nicotinamide adenine dinucleotide), which is required for glycolysis to continue. Lactate fermentation can occur under both aerobic and anaerobic conditions, contributing to the metabolic flexibility of cancer cells.
Oxidative Phosphorylation (OXPHOS): Some cancers rely on oxidative phosphorylation for energy production rather than aerobic glycolysis. This is more typical in certain tumor types and can involve efficient utilization of mitochondrial function.
Glutamine Metabolism: Glutamine is an amino acid that cancer cells can use as an alternative substrate for energy production and as a source of carbon and nitrogen for biomass synthesis. Some cancer cells exhibit high dependence on glutamine metabolism.
Fatty Acid Oxidation (FAO): In addition to glycolysis, cancer cells may enhance fatty acid oxidation to meet their energy needs. This is particularly relevant in certain cancers where lipid metabolism is upregulated. This could be a problem for ketogenic diet solutions as it increase Fatty Acid availability in the body. This is why a meat based diet which is higher in proteins and lower in fats than typical keto diet is recommended.