(1) Biological: Many different kinds of bacteria that are known to make people sick have been found in insects including E. coli and Campylobacter. In addition to these bacteria, viruses, parasites, and fungi are also possible forms of biological contamination.

(2) Insect-based novel foods are negatively impacted by the safety of the composition and quality of feed used to raise the insects and their rearing conditions.

(3) Insects can bioaccumulate chemical residues and heavy metals, and produce harmful substances. Insects can contain anti-nutrients that interfere with physiological processes.

(4) The most well-known factor concerning insects related to public health is their role as vectors of pathogens. Arthropods can transmit several infectious pathogens (e.g., bacteria, parasites, protozoa and viruses) resulting in more than 700,000 deaths per year from vector-borne diseases worldwide