There's theory, and then there's clinical reality. This study has already been done. In the late 2010s, PCSK-9 inhibitors came onto the market as a new cholesterol-lowering option for people who maxed out on statins or who couldn't tolerate them.
The ODYSSEY OUTCOMES trial (published in the NEJM here in 2018) actually addressed the safety concern of extremely low cholesterol levels. 20-25 mg/dL is considered physiologic, the amount you must have to maintain your cells' cell membranes and such structures. These guys dropped ~9,500 (and other 9,500ish took placebo) patients to the 25-50 range for an average follow-up time of 2.2 years.
This guy is alleging nerve damage, but none was documented in this study. Check table 3. The rates of neurocognitive disorders in the trial group and the placebo group are essentially identical. The drug dropping LDL levels that low didn't cause anything like what this man in the Twitter video is suggesting.
This is a huge study with a long follow-up time. It's pretty much gold standard quality data, and disproves the random guy on the internet pretty conclusively.
This man talks like he understands. He doesn't. He's confusing cholesterol with fatty acids. He talks about the differences between saturated fats (fatty acids, not cholesterol) and unsaturated fats, and suggests it causes Alzheimers. It doesn't. Alzheimer's is caused by misfolding proteins called beta amyloids, not by fatty acids or cholesterol. And he alleges dementia didn't exist before 1979 and the characterization of Alzheimers. That's clearly false. Crazy old people losing their minds as they age have been known and described for millennia.
This man is why you don't listen to the internet doctors. You go to a real one.
Agreed. I knew the author is either not intelligent or selling clicks etc.
from the myelin is made of 100% cholesterol. The specialized protective sheath covering the most important delicate nerves in your body is just pure fat? Cmon nobody should fall for that.
There's theory, and then there's clinical reality. This study has already been done. In the late 2010s, PCSK-9 inhibitors came onto the market as a new cholesterol-lowering option for people who maxed out on statins or who couldn't tolerate them.
The ODYSSEY OUTCOMES trial (published in the NEJM here in 2018) actually addressed the safety concern of extremely low cholesterol levels. 20-25 mg/dL is considered physiologic, the amount you must have to maintain your cells' cell membranes and such structures. These guys dropped ~9,500 (and other 9,500ish took placebo) patients to the 25-50 range for an average follow-up time of 2.2 years.
This guy is alleging nerve damage, but none was documented in this study. Check table 3. The rates of neurocognitive disorders in the trial group and the placebo group are essentially identical. The drug dropping LDL levels that low didn't cause anything like what this man in the Twitter video is suggesting.
This is a huge study with a long follow-up time. It's pretty much gold standard quality data, and disproves the random guy on the internet pretty conclusively.
This man talks like he understands. He doesn't. He's confusing cholesterol with fatty acids. He talks about the differences between saturated fats (fatty acids, not cholesterol) and unsaturated fats, and suggests it causes Alzheimers. It doesn't. Alzheimer's is caused by misfolding proteins called beta amyloids, not by fatty acids or cholesterol. And he alleges dementia didn't exist before 1979 and the characterization of Alzheimers. That's clearly false. Crazy old people losing their minds as they age have been known and described for millennia.
This man is why you don't listen to the internet doctors. You go to a real one.
Agreed. I knew the author is either not intelligent or selling clicks etc. from the myelin is made of 100% cholesterol. The specialized protective sheath covering the most important delicate nerves in your body is just pure fat? Cmon nobody should fall for that.
Doctors are the problem. The larger problem is that doctors are taught what they know by the pharmaceutical industry.
Spitting facts.