I'm not a psychologist nor do I know anything much medically, but I have lived life and saw many things. 'I don't think' a person becomes Bipolar overnight or overtime, I think you either always were Bipolar or you never were Bipolar. As for the PMDD, this is a great possibility as I've met other women who have struggled with it or PMS. But there comes a time in both 'not all people' a man and woman's life when they reach a crossroad. It usually strikes around late 30's to mid 40's. Most people call it a mid-life crisis.

They feel that their 'youth' is slipping away. Feelings of 'what did I accomplish' and 'where am I going.' No longer feeling attractive among others much less to their spouse. Feeling that soon they will be over the 'hump' and speeding towards 'old age.' I know, I was there myself. So what do you do about it?

 It takes a patient person with lots of love to help them through. Perhaps you could take her out to buy a new outfit/dress. Have her get all dolled up and then take her out for the evening. Tell her how you want to show the world that you have the most beautiful woman in the world, then let her flaunt it to an extent. Be a gentleman in everything. Women during this time want to feel appreciated. After work, (I know you're tired) ask if you could help with the dishes. Then later sit down and watch a movie together. If you join something for yourself, include her in your decision and ask if she'd like to join too. Don't forget to tell her that 'you' have needs too and that you want to stay in shape. Tell her that you want to look handsome for her and you don't want to let yourself go either.

 But most of all, sit down and TALK and ask her what it is that she wants/needs. Remind her how much you LOVE HER and how you want to spend the rest of your life with her. I believe she is suffering a mid-life crisis. It is the void she cannot fill, the thing she is searching for. Remember, God said, "THIS TOO SHALL PASS." Given time, understanding and love, she should be the wife you remember. AND I would check out the PMDD just in case. Let's cross what it isn't so you can work on what it really is. AND she may be Bipolar but just never knew it. There would have been plenty of signs along the way through the years that you simply didn't notice. But right now, I go for the mid-life crisis. Good luck and God bless my friend.