HOW TO TREAT YOURSELF FROM MONKEYPOX (From my own research)

• 1. Inhibition of Viral Entry and Attachment

Flavonoids

• Most Flavonoids and other phytochemicals, have a very low absorption rate between 0 and 5% Purchasing nano or liposomal versions along with peperine enhances absorption to nearly 100%

  • Quercetin

    • Mechanism: Quercetin interferes with the virus's ability to bind to and enter host cells. It can stabilize cell membranes and block viral adhesion.
    • Dosage: 500-1,000 mg/day, divided into 2-3 doses. Higher doses may be used in acute situations under professional supervision.
    • Toxicity: Generally well-tolerated. High doses may cause gastrointestinal upset, headache, or fatigue. Long-term high doses could impact kidney function.
    • Cautions: Can interact with certain medications, including blood thinners (e.g., warfarin) and some antibiotics, potentially affecting their efficacy.

  • Catechins (e.g., Epigallocatechin Gallate - EGCG)

    • Mechanism: EGCG prevents the attachment of viruses to host cells and inhibits viral entry. It also has anti-inflammatory and antioxidant properties.
    • Dosage: 200-400 mg/day. Higher doses may be considered for acute symptoms with medical guidance.
    • Toxicity: Typically safe in moderate doses. High doses may affect liver function or cause gastrointestinal disturbances. May interact with anticoagulant medications.
    • Cautions: EGCG can interact with anticoagulants and antiplatelet drugs, increasing bleeding risk. It may also affect the absorption of some medications.

• 2. Disruption of Viral Replication

Saponins

• Ginsenosides (from Panax Ginseng)
  • Mechanism: Ginsenosides can inhibit viral replication by disrupting viral enzyme activities and modulating the host cell’s antiviral responses. They also enhance the immune response.
  • Dosage: 200-400 mg/day. Acute dosing should be managed by a healthcare professional.
  • Toxicity: Generally safe. High doses may cause insomnia, nervousness, gastrointestinal issues, or affect blood sugar levels.
  • Cautions: Ginsenosides may interact with anticoagulants, diabetes medications, and immunosuppressants. Use cautiously with other supplements that affect blood sugar or immune function.

Tannins

• Ellagic Acid
  • Mechanism: Ellagic acid inhibits viral replication by blocking viral RNA/protein synthesis. It also has antioxidant properties that protect host cells from damage.
  • Dosage: 100-300 mg/day. Acute treatment may involve higher doses under medical supervision.
  • Toxicity: Usually well-tolerated. High doses might cause gastrointestinal issues or allergic reactions. Limited data on long-term high-dose safety.
  • Cautions: Can inhibit the absorption of certain minerals (e.g., iron). Caution is advised if taken with iron supplements or medications affecting mineral absorption.

• 3. Modulation of Immune Response

Terpenes

• Limonene

  • Mechanism: Limonene enhances immune function and has direct antiviral properties. It may help modulate inflammatory responses and support overall immune health.
  • Dosage: 250-500 mg/day. Acute treatment should involve careful dosing.
  • Toxicity: Generally safe at recommended doses. High doses may cause gastrointestinal issues or skin irritation.
  • Cautions: Limonene may interact with medications metabolized by the liver’s cytochrome P450 enzymes. Caution is advised if taking drugs processed by these enzymes.

• Thymol

  • Mechanism: Thymol boosts immune function and exhibits direct antiviral activity, potentially reducing viral load and inflammation.
  • Dosage: Typically used in topical applications at concentrations of 0.5%-2%. Oral or high doses should be managed carefully.
  • Toxicity: Essential oil can be irritating. High doses may lead to nausea, vomiting, or liver toxicity. Use cautiously in children or during pregnancy.
  • Cautions: Avoid excessive use, particularly with other irritants or in sensitive individuals.

• 4. Protease Inhibition

Glycyrrhizin (from Licorice Root)

• Mechanism: Glycyrrhizin inhibits viral proteases, crucial for viral maturation and replication. It can reduce viral load and enhance the host’s antiviral response.
• Dosage: 100-400 mg/day. Acute situations might require higher doses under supervision.
• Toxicity: Long-term or high doses can cause hypertension, hypokalemia, and fluid retention. Not recommended for individuals with cardiovascular issues, high blood pressure, or renal problems.
• Cautions: Glycyrrhizin may interact with antihypertensive medications, diuretics, and corticosteroids. Caution is needed for those with cardiovascular issues or on medications affecting blood pressure.

Quercetin

• Mechanism: Quercetin, a flavonoid found in many fruits and vegetables, has multiple bioactive effects, including antioxidant, anti-inflammatory, and antiviral properties.

• Antioxidant Action: Neutralizes free radicals, reducing oxidative stress and protecting cells.

• Anti-inflammatory Action: Inhibits inflammatory pathways and reduces cytokine production.

• Antiviral Action: Interferes with viral replication by blocking viral entry and modulating host cell responses.

• Indirect Protease Inhibition: While not a direct protease inhibitor, quercetin may affect viral protease activity indirectly by modulating cellular pathways involved in viral replication. This can influence the processing of viral proteins necessary for replication.

  • Cautions: High doses may cause gastrointestinal discomfort.

• 5. Anthelmintic Properties

Wormwood (Artemisia absinthium)

• Mechanism: Contains artemisinin and other compounds with antiviral and antiparasitic properties. It may interfere with viral replication and modulate immune responses.
• Dosage: Typically 200-400 mg/day of standardized extract. For acute treatment, dosages may vary, and professional guidance is essential.
• Toxicity: Generally safe in recommended doses. High doses may cause nausea, vomiting, or neurological effects. Prolonged use can be toxic.
• Cautions: Combining wormwood with anthelmintics like ivermectin or fenbendazole may increase the risk of adverse effects or toxicity. Wormwood may also interact with drugs metabolized by the liver’s cytochrome P450 system.

Garlic (Allium sativum)

• Mechanism: Contains allicin, which has antimicrobial, antiviral, and anthelmintic properties. It supports immune responses and disrupts the metabolism of pathogens.
• Dosage: 600-1,200 mg of aged garlic extract daily. Acute treatment might involve higher doses with medical advice.
• Toxicity: Generally safe. High doses may cause gastrointestinal upset, heartburn, or allergic reactions.
• Cautions: Garlic can enhance the effects of anticoagulants (e.g., warfarin), increasing bleeding risk. Use with caution if on blood thinners or undergoing surgery.

Black Walnut (Juglans nigra)

• Mechanism: Contains juglone, which exhibits anthelmintic and antimicrobial properties. It disrupts the metabolic processes of parasites and pathogens.
• Dosage: Typically 500-1,000 mg/day in extract form. Acute treatment dosages should be managed by a healthcare provider.
• Toxicity: Generally safe but can cause gastrointestinal discomfort. High doses may lead to liver toxicity and allergic reactions.
• Cautions: Black walnut may interact with anticoagulants and medications metabolized by the liver. Caution is advised if taking other drugs that affect liver metabolism.

Ivermectin

• Mechanism: Binds to parasite muscle and nerve cells, causing paralysis and death. Ivermectin may also exhibit some antiviral effects by inhibiting viral replication.
• Dosage: Typically 150-200 µg/kg body weight, administered as a single dose. Dosage may vary based on specific indications and should be adjusted according to clinical guidance.
• Toxicity: Generally well-tolerated. High doses or prolonged use may cause dizziness, gastrointestinal issues, or neurological effects.
• Cautions: Caution advised when used with other medications that affect liver enzymes, as it can interact with drugs metabolized by cytochrome P450.

Fenbendazole

• Mechanism: Disrupts the parasite’s microtubule formation, leading to its death. Fenbendazole also has potential antiviral effects by affecting viral replication.
• Dosage: Commonly 10-50 mg/kg body weight per day, typically for 3 days. Dosage may vary based on clinical indications.
• Toxicity: Generally safe at recommended doses. High doses may cause gastrointestinal upset or liver issues.
• Cautions: Use with caution if combined with other drugs that affect liver metabolism. Limited data on interactions with other medications.

Purchase Links from what I take and know works.

• 1. Nano Cucumin: https://a.co/d/cACbW0s
• 2. Nano EGCG: https://a.co/d/1ccmzo6
• 3. Nano Quercetin: https://a.co/d/b7LT41d
• 4. Fenbendazole: https://fenben.pro/product/fenbendazol-powder/

Peer reviewed sources (Mostly Meta-Analyses)

• 1. https://doi.org/10.3390/ph17060692
• 2. https://doi.org/10.3389/fnut.2021.606782
• 3. https://doi.org/10.1016/j.bcp.2016.09.029
• 4. https://doi.org/10.1016/j.rechem.2023.101013
• 5. https://doi.org/10.1016/j.nutos.2021.12.004
• 6. https://doi.org/10.3390/pharmaceutics15020348
• 7. https://doi.org/10.1007/s11101-023-09855-2