I told my dr that the unremitting joint pain caused by the statin was making daily life a challenge. I now take half the dose and joint pain is gone. We had a discussion about alzheimers and the outer part of the brain being almost all cholesterol. She warned me of being helpless from a stroke. I need a dr at my age. Luckily she knew I wouldn't take the clot shot and didn't argue, so there's that.